Amyotrophic lateral sclerosis: clinical analysis of 78 cases from Fortaleza (Northeastern Brazil)
Arq. neuropsiquiatr
;
57(3B): 761-74, set. 1999. tab, graf
Artículo
en Inglés
| LILACS
| ID: lil-247383
RESUMO
We report on the clinical characteristics of amyotrophic lateral sclerosis (ALS) in Fortaleza (Northeastern Brazil). For this, we analyzed retrospectively (from 1980 to 1999) 78 cases of ALS from the Service of Neutrology of the University Hospital of Fortaleza diagnosed clinically and laboratorially (EMG, muscle biopsy, myelography, blood biochemistry, muscle enzymes and cranio-cervical X-ray). The results showed that they were mostly sporadic ALS (76/78), and they were divided into definite (n=36), probable (n=20), possible (n=15) and suspected (n=7), according to the level of diagnostic certainty. They were also subdivided into juvenile (n=17), early-onset adult (n=18), age-specific (n=39) and late-onset (n=4) groups. Clinically, they presented as initals symptoms, principally, asymmetrical (30/78) and symmetrical (24/78) weakness of extremities, besides bulbar signs, fasciculations, and atrophy. Curiously, pain as first symptom occurred in an expessive fashion (17/78). The predominant initial anatomic site, in this series, was the spinal cord, and mainly affecting the arms. As to the symptom accrual from region to region, this occurs more quickly in contiguous areas, and fasciculations are predominant when bulbar region was associated.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Esclerosis Amiotrófica Lateral
Tipo de estudio:
Estudio observacional
/
Factores de riesgo
Límite:
Adolescente
/
Adulto
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Arq. neuropsiquiatr
Asunto de la revista:
Neurología
/
Psiquiatria
Año:
1999
Tipo del documento:
Artículo
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