IgG recognizing 21-24 kDa and 30-33 kDa tachyzoite antigens show maximum avidity maturation during natural and accidental human toxoplasmosis
Rev. Inst. Med. Trop. Säo Paulo
;
41(5): 297-303, Sept.-Oct. 1999. graf, tab
Artículo
en Inglés
| LILACS
| ID: lil-250203
RESUMO
We describe the avidity maturation of IgGs in human toxoplasmosis using sequential serum samples from accidental and natural infections. In accidental cases, avidity increased continuously throughout infection while naturally infected patients showed a different profile. Twenty-five percent of sera from chronic patients having specific IgM positive results could be appropriately classified using exclusively the avidity test data. To take advantage of the potentiality of this technique, antigens recognized by IgG showing steeper avidity maturation were identified using immunoblot with KSCN elution. Two clusters of antigens, in the ranges of 21-24 kDa and 30-33 kDa, were identified as the ones that fulfill the aforementioned avidity characteristics
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Toxoplasma
/
Inmunoglobulina G
/
Toxoplasmosis
/
Afinidad de Anticuerpos
/
Antígenos de Protozoos
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Límite:
Animales
/
Humanos
Idioma:
Inglés
Revista:
Rev. Inst. Med. Trop. Säo Paulo
Asunto de la revista:
Medicina Tropical
Año:
1999
Tipo del documento:
Artículo
País de afiliación:
Uruguay
Similares
MEDLINE
...
LILACS
LIS