Predictive value of the acid fast smear for detection of Mycobacterium tuberculosis in respiratory specimens in a Reference Center of HIV/Aids in Rio de Janeiro, Brazil
Mem. Inst. Oswaldo Cruz
;
94(6): 787-90, Nov.-Dec. 1999. tab
Artículo
en Inglés
| LILACS
| ID: lil-251340
RESUMO
In order to evaluate the predictive value of acid fast bacilii (AFB) smear for the diagnosis of Mycobacterium tuberculosis in respiratory specimens in a setting with a high prevalence of Aids and an unknown prevalence of nontuberculous mycobacteria (NTM), we retrospectively examined specimens cultured for mycobacteria between 1 September 1993 and 30 September 1994 and medical records of patients with positive culture in a General Hospital, Aids reference in Rio de Janeiro, Brazil. Seventy three per cent (1517/2077) of samples were respiratory specimens and mycobacteria were recovered from 20.6 percent (313/1517) of these. M. tuberculosis was identified in 94.2 percent (295/313) and NTM in 5.8 percent (18/313). The yield of positive AFB smear and of positive culture was 6.1 pecent (93/1517) and 20.6 percent (313/1517), respectively. The positive predictive value (PPV) of AFB for M. tuberculosis was 98.4 percent in expectorated sputum and 96.4 percent in bronchoalveolar lavage. Forty four percent (130/295) of specimens with positive culture for M. tuberculosis and 66.7 percent (12/18) for NTM were from patients HIV positive. The conclusion was that in our study population, the PPV of AFB for M. tuberculosis in respiratory specimens was high and the prevalence of NTM was low despite the high prevalence of HIV positive
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Manejo de Especímenes
/
Esputo
/
Tuberculosis Pulmonar
/
Infecciones Oportunistas Relacionadas con el SIDA
/
Mycobacterium tuberculosis
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio de prevalencia
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
1999
Tipo del documento:
Artículo
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