Spontaneous Kanamycin-resistant Escherichia coli mutant with altered periplasmic oligopeptide permease protein (OPPA) and impermeability to aminoglycosides
Rev. microbiol
;
30(2): 153-6, abr.-jun. 1999. ilus, tab
Artículo
en Portugués, Inglés
| LILACS
| ID: lil-257213
ABSTRACT
A spontaneous kanamycin-resistant Escherichia coli mutant, showing cross resitance to five other aminoglycosides and absence of the OppA protein was isolated. [3H]- dihydrostreptomycin uptake is reduced in this mutant, implying that the oligopeptide transport system in involved in accumulation of aminoglucosides, although apparently not related with aminoglycoside permeability alteration due to bacterial adaptation to osmotic changes.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Oligopéptidos
/
Proteínas de Transporte de Membrana
/
Resistencia a la Kanamicina
/
Proteínas
/
Periplasma
/
Escherichia coli
/
Aminoglicósidos
Idioma:
Inglés
/
Portugués
Revista:
Rev. microbiol
Asunto de la revista:
Microbiologia
Año:
1999
Tipo del documento:
Artículo
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