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El estudio HERS conmociona a la terapia de sustitución hormonal / HERS study disturbs hormonal replacement therapy
Cano S., Antonio; Blumel M., Juan Enrique.
  • Cano S., Antonio; Hospital Universitario de Valencia.
  • Blumel M., Juan Enrique; Universidad de Chile. Facultad de Medicina. Hospital Barros Luco-Trudeau.
Rev. méd. Chile ; 128(1): 98-104, ene. 2000. ilus
Artículo en Español | LILACS | ID: lil-258094
RESUMO
Cardiovascular protection of hormonal replacement therapy was considered a fact. The effects of estrogens on lipid levels and vascular health gave biological support to estrogen cardioprotection. The recently published HERS study showing no protective effects of estrogen and progesterone replacement therapy on the risk of myocardial infarction or coronary deaths is provoking perplexity. These surprising results may have several causes such as the use of progesterone, the associated use of cardioprotective agents or the short observation period. However, the study results scope is rectricted to secondary prevention. These cannot be extrapolated to frequent conditions of postmenopausal women such as primary prevention or sequential schemes. Likewise, this investigation underscores the importance of a critical and continued evaluation of apparently well established therapeutic approaches
Asunto(s)
Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Terapia de Reemplazo de Estrógeno / Posmenopausia Límite: Femenino / Humanos Idioma: Español Revista: Rev. méd. Chile Asunto de la revista: Medicina Año: 2000 Tipo del documento: Artículo

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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Terapia de Reemplazo de Estrógeno / Posmenopausia Límite: Femenino / Humanos Idioma: Español Revista: Rev. méd. Chile Asunto de la revista: Medicina Año: 2000 Tipo del documento: Artículo