Effect of n-acetylcysteine in a random skin flap after administration of nicotine, in the rat
Folha méd
; 117(3): 209-11, nov.-dez. 1998. ilus, graf
Article
en En
| LILACS
| ID: lil-260507
Biblioteca responsable:
BR1.1
RESUMO
This study analyzed the perfusion of a random skin flap, after nicotine injection and administration of N-acetylcysteine (NAC). A skin flap was elevated after 6 weeks of nicotine administartion and the percentage of necrosis was determined thereafter, as well as malondialdehyde (MDA) in 4 selected skin areas and in serum. Both nicotine and NAC elicited elevation in MDA levels in the skin samples. Nicotine also led to elevation in serum MDA levels and in the percentage of flap necrosis. NAC did not improve the viability of the flap.
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Índice:
LILACS
Asunto principal:
Acetilcisteína
/
Colgajos Quirúrgicos
/
Depuradores de Radicales Libres
/
Agonistas Nicotínicos
/
Nicotina
Límite:
Animals
Idioma:
En
Revista:
Folha méd
Asunto de la revista:
MEDICINA
Año:
1998
Tipo del documento:
Article