Carcinoma de próstata com metástase óssea em cäo / Prostate carcinoma with bone metastasis in a dog

ABSTRACT

This report describes a case of prostate carcinoma with metastasis to bone and other organs in a 10-year old Cocker Spaniel dog. The animal had history of difficult walking and evacuation and hind limbs flaccid paralysis. Clinically, abdominal pain and very full urinary bladder, were found. The urine had cloudy aspect and phosphate crystals and granular casts. The radiologic examination of abdominal cavity showed and enlargement of the prostate and lost radiologic density of the last lumbar vertebra. The animal was euthanized. Grossly, the prostate was enlarged, irregular, nodular and asymmetrical, with firm consistence. On cut surface, it was whitish with brown spots. The neoplastic tissue involved the iliac lymph nodes and last lumbar vertebra besides the pulmonary metastasis. This mass reached the urethra and urinary bladder inducing unilateral hydronephrosis in the left kidney. Histologically, the diagnosis of poorly differentiated prostate carcinoma was made