Pathophysiology of cancer cachexia
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo
;
55(5): 181-93, Sept. 2000.
Artículo
en Inglés
| LILACS
| ID: lil-275171
ABSTRACT
Cancer cachexia is a frequent complication observed in patients with malignant tumors. Although several decades have passed since the first focus on the metabolic dysfunction's associated with cancer, few effective therapeutic interventions have been successfully introduced into the medical armamentarium. The present study thoroughly reviews the basic pathophysiology of cancer cachexia and the treatment options already investigated in that field. Experimental and clinical studies were evaluated individually in order to clarify the intricate alterations observed in tumor-bearing patients. The difficulties in introducing sound and effective nutritional support or metabolic manipulation to reverse cancer cachexia are outlined in this review.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Caquexia
/
Neoplasias
Tipo de estudio:
Revisiones Sistemáticas Evaluadas
Límite:
Animales
/
Humanos
Idioma:
Inglés
Revista:
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo
Asunto de la revista:
Medicina
Año:
2000
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade de Sao Paulo/BR
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