Antigen incorporation on Cryptosporidium parvum oocyst walls
Mem. Inst. Oswaldo Cruz
;
96(2): 233-5, Feb. 2001. ilus
Artículo
en Inglés
| LILACS
| ID: lil-281573
ABSTRACT
Cryptosporidium parvum oocysts are the infective stages responsible for transmission and survival of the organism in the environment. In the present work we show that the oocyst wall, far from being a static structure, is able to incorporate antigens by a mechanism involving vesicle fusion with the wall, and the incorporation of the antigen to the outer oocyst wall. Using immunoelectron microscopy we show that the antigen recognized by a monoclonal antibody used for diagnosis of cryptosporidiosis (Merifluor®, Meridian Diagnostic Inc.) could be found associated with vesicles in the space between the sporozoites and the oocysts wall, and incorporated to the outer oocyst wall by an unknown mechanism
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Oocitos
/
Cryptosporidium parvum
/
Antígenos de Protozoos
Tipo de estudio:
Estudio diagnóstico
Límite:
Animales
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
2001
Tipo del documento:
Artículo
País de afiliación:
España
Institución/País de afiliación:
Universidad de Granada/ES
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