Skin reactions to thimerosal and Leishmania in dogs from a leishmaniasis endemic area: it is better to keep them apart
Mem. Inst. Oswaldo Cruz
;
96(5): 679-681, July 2001. tab
Artículo
en Inglés
| LILACS
| ID: lil-289356
RESUMO
Positive Montenegro's skin test is a delayed type hypersensitivity reaction widely used as indicative of previous infection with Leishmania in both humans and dogs. Montenegro's antigen consists of a crude Leishmania antigen solution, usually containing thimerosal as preserving agent. In this work it is shown that a large proportion of dogs (11 out of 56) examined in an endemic area of leishmaniasis presented induration at the site of injection of a diluent containing thimerosal alone. This clearly demonstrates that thimerosal leads to a high number of false positive skin reactions in dogs and that its use in Montenegro's skin test antigenic preparations should be avoided
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Conservadores Farmacéuticos
/
Piel
/
Timerosal
/
Leishmaniasis
/
Enfermedades de los Perros
/
Leishmania
Tipo de estudio:
Estudio diagnóstico
Límite:
Animales
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
2001
Tipo del documento:
Artículo
/
Documento de proyecto
País de afiliación:
Brasil
Institución/País de afiliación:
Centro de Referência em Doenças Endêmicas Pirajá da Silva/BR
/
Fundaçäo do Instituto Oswaldo Cruz/BR
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