Juvenile idiopathic inflammatory myopathies: the value of magnetic resonance imaging in the detection of muscle involvement
São Paulo med. j
;
118(2): 35-40, Mar. 2000. tab, graf
Artículo
en Inglés
| LILACS
| ID: lil-289847
RESUMO
CONTEXT One of the major current challenges related to juvenile idiopathic inflammatory myopathy is the search for highly sensitive and specific non-invasive methods for diagnosis as well as for follow-up. OBJECTIVES:
The aim of our study was to describe typical magnetic resonance imaging findings and to investigate the usefulness of this method in detecting active muscle disease in juvenile dermatomyositis and juvenile systemic lupus erythematosus patients.DESIGN:
Transverse study, blinded assessment.SETTING:
University referral unit (Pediatric Rheumatology section, Department of Pediatrics, Universidade Federal de Sao Paulo / Escola Paulista de Medicina). SAMPLE Thirteen patients (9 girls) with dermatomyositis, as well as 13 patients (12 girls) with juvenile systemic lupus erythematosus and 10 normal children (5 girls), were enrolled in the study. MAIN MEASUREMENTS Qualitative and quantitative analyses of gluteus maximus, quadriceps, adductors and flexors were performed and evaluated by two radiologists, blinded to all clinical information. Spin-echo in T1, DP, T2 and IR was used in all MRI images.RESULTS:
The different muscle groups presented non-uniform involvement in the patients. The patients with dermatomyositis presented acute and chronic muscular alterations, while those with lupus presented only chronic myopathy, especially atrophy. In the dermatomyositis group, the major alterations were found in the gluteus and flexor regions (signal intensity and fat replacement). The signal intensity was increased in all acute myopathies.CONCLUSION:
The qualitative and quantitative resonance analyses are useful in detecting clinically active disease in patients with dermatomyositis
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Imagen por Resonancia Magnética
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Dermatomiositis
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Lupus Eritematoso Sistémico
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Músculos
Tipo de estudio:
Ensayo Clínico Controlado
/
Estudio diagnóstico
/
Estudio observacional
/
Investigación cualitativa
Límite:
Adolescente
/
Niño
/
Child, preschool
/
Femenino
/
Humanos
Idioma:
Inglés
Revista:
São Paulo med. j
Asunto de la revista:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicina
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Año:
2000
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Federal de Sao Paulo/BR
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