Regulation of the renal proximal tubule second sodium pump by angiotensins
Braz. j. med. biol. res
;
34(8): 1079-1084, Aug. 2001. ilus
Artículo
en Inglés
| LILACS
| ID: lil-290157
RESUMO
For several years it was believed that angiotensin II (Ang II) alone mediated the effects of the renin-angiotensin system. However, it has been observed that other peptides of this system, such as angiotensin-(1-7) (Ang-(1-7)), present biological activity. The effect of Ang II and Ang-(1-7) on renal sodium excretion has been associated, at least in part, with modulation of proximal tubule sodium reabsorption. In the present review, we discuss the evidence for the involvement of Na+-ATPase, called the second sodium pump, as a target for the actions of these compounds in the regulation of proximal tubule sodium reabsorption
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Sodio
/
Angiotensina I
/
Angiotensina II
/
ATPasa Intercambiadora de Sodio-Potasio
/
Espacio Extracelular
/
Túbulos Renales Proximales
Límite:
Animales
Idioma:
Inglés
Revista:
Braz. j. med. biol. res
Asunto de la revista:
Biologia
/
Medicina
Año:
2001
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Federal do Rio de Janeiro/BR
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