Hepatitis aguda por virus A, E y no A-E en adultos chilenos a fines de los años 90 / Acute hepatitis caused by virus A, E and non A-E in chilean adults
Rev. méd. Chile
;
129(5): 523-30, mayo 2001. tab, graf
Artículo
en Español
| LILACS
| ID: lil-295254
ABSTRACT
Background:
Sanitary and socioeconomic changes and the identification of new causative virus, have changed the epidemiology of hepatitis in Chile.Aim:
To study the natural history of acute hepatitis caused by virus A, E and non A-E in Chilean adults. Patients andmethods:
A special study protocol was followed for patients with a clinical picture of acute hepatitis. Anti HAV IgM, anti HBc IgM, anti HEV IgG and IgM and Anti HCV antibodies were determined by ELISA.Results:
Fifty nine patients (30 male), aged 15 to 58 years old were studied. Eighty nine percent had jaundice and 50 to 70 percent had malaise and abdominal pain. Virus A was positive in 80 percent, virus E in 7 percent. In 14 percent of patients, all viral markers were negative. The evolution was typical in 78 percent, biphasic in 14 percent and cholestatic in 5 percent. One patient had a prolonged and one a fulminant course. Mean ALT was 1148 U/l and mean total bilirubin was 5.5 mg/dl. Seventy three percent of cases occurred during early winter and spring and 27 percent during summer and early autumm.Conclusions:
The main etiology of acute viral hepatitis in Chile is virus A and most cases occur during the rainy season. Clinical features of hepatitis non A-E are similar to enteral transmission forms
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Hepatitis E
/
Hepatitis A
Tipo de estudio:
Guía de Práctica Clínica
/
Estudio pronóstico
Límite:
Adolescente
/
Adulto
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Chile
Idioma:
Español
Revista:
Rev. méd. Chile
Asunto de la revista:
Medicina
Año:
2001
Tipo del documento:
Artículo
/
Documento de proyecto
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