Worm load and septal fibrosis of the liver in Capillaria hepatica-infected rats
Mem. Inst. Oswaldo Cruz
;
96(7): 1001-1003, Oct. 2001. ilus
Artículo
en Inglés
| LILACS
| ID: lil-298898
ABSTRACT
Inocula, varying from 15 to 1,000 embryonated Capillaria hepatica eggs, were administered to young adult rats by gastric tube, in an attempt to investigate the influence of worm load in the production of septal fibrosis of the liver. Low doses of 15, 30 or 50 eggs were sufficient to produce septal fibrosis, but it appeared with variable degrees of intensity and always with focal distribution. Septal fibrosis became diffuse, progressive with time, and already well developed 40 days after infection, when 100 eggs or more were administered. However, higher inocula (200, 500 and 1,000 eggs) did not intensify septal fibrosis, although the number of parasitic focal lesions proportionally augmented
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Capillaria
/
Infecciones por Enoplida
/
Cirrosis Hepática Experimental
/
Parasitosis Hepáticas
Tipo de estudio:
Estudio pronóstico
Límite:
Animales
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
2001
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Fiocruz/BR
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