Carga viral en liquido cefalorraquideo de pacientes hemofílicos HIV-1 positivos bajo tratamiento con HAART / Cerebrospinal fluid viral load in HIV-1 positive hemophilic patients treated with HAART
Medicina (B.Aires)
; 61(6): 821-4, 2001. tab
Article
en Es
| LILACS
| ID: lil-300784
Biblioteca responsable:
BR1.1
RESUMO
As HIV seropositive patients with undetectable CSF viral load have a lower likelihood of developing neurologic disease, the determination of CSF viral load levels may be useful to evaluate the efficacy of HAART. We compared plasma viral load levels with HIV-1 RNA CSF levels in 18 hemophilic patients without neurocognitive involvement under HAART. We detected a significant correlation between plasma viral load levels and CSF viral load levels. Fourteen patients with undetectable plasma viral load had undetectable RNA HIV-1 CSF levels as well. Four patients with detectable plasma viral load had detectable HIV-RNA in CSF, but the latter were significantly lower. Viral load is usually lower in non-blood fluids and HAART decreases the viral load in CSF as well as in blood.
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Índice:
LILACS
Asunto principal:
ARN Viral
/
Infecciones por VIH
/
VIH-1
/
Carga Viral
/
Terapia Antirretroviral Altamente Activa
/
Hemofilia A
Límite:
Humans
Idioma:
Es
Revista:
Medicina (B.Aires)
Asunto de la revista:
MEDICINA
Año:
2001
Tipo del documento:
Article