Efeito do choque hipovolêmico na anastomose do intestino delgado de ratos / Effect of hypovolemic shock in anastomose of small intestine of rats
Arq. gastroenterol
;
38(2): 116-124, abr.-jun. 2001. tab, graf
Artículo
en Portugués
| LILACS
| ID: lil-305367
RESUMO
OBJECTIVE:
Study the effect of hypovolemic shock on small intestinal anastomose in adult rats.METHOD:
Ninety male rats were randomly divided into five groups standard, hypovolemic shock, anastomose alone, hypovolemic shock + anastomose and hypovolemic shock + anastomose + blood reinfusion. Hypovolemic shock was achieved by bleeding 30% of the blood volume of the animal. A single layer extramucosal intestinal anastomose was performed. Following intestinal anastomose, the blood volume was restored in group shock, anastomose and blood reinfusion, using heparinized autologous. RESULTS ANDCONCLUSION:
In the experimental model used, hypovolemic shock provoked histological lesions to the mucosa and increased colagen fiber deposition into the submucosa in the region of intestinal anastomose which were progressive with post-operative period. In addition, when the hypovolemic shock group were pressure tested there was a tendency towards a weakening of the intestinal wall at day 7 which became more evident at day 21 as compared to the control groups.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Choque
/
Intestino Delgado
Tipo de estudio:
Estudio de etiología
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Animales
Idioma:
Portugués
Revista:
Arq. gastroenterol
Asunto de la revista:
Gastroenterologia
Año:
2001
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Federal de São Paulo/BR
/
Universidade do Estado do Pará/BR
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