Charaterization of Leishmania major Friedlin Telomeric Terminus
Mem. Inst. Oswaldo Cruz
;
97(3): 343-346, Apr. 2002. ilus, tab
Artículo
en Inglés
| LILACS
| ID: lil-307962
RESUMO
Here we have characterized Leishmania major (Friedlin) telomeric terminus (the very end) using recombinants obtained by a vector-adaptor cloning protocol. As in L. donovani, the last nine nucleotides of L. major terminus are 5'-GGTTAGGGT-OH 3', differing from Trypanosoma cruzi and T. brucei terminus 5'GGGTTAGGG-OH 3', thus indicating that these sequences are genus specific. We have also made a comparative analysis between L. major and L. donovani telomere-associated sequences, and described a novel non-repeated telomeric associated sequence common to L. major low molecular weight chromosomal bands
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Telómero
/
Leishmania major
Límite:
Animales
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
2002
Tipo del documento:
Artículo
/
Documento de proyecto
País de afiliación:
Venezuela
Institución/País de afiliación:
Universidad Central de Venezuela/VE
Similares
MEDLINE
...
LILACS
LIS