Experimental Neuroschistosomiasis: inadequacy of the murine model
Mem. Inst. Oswaldo Cruz
;
97(4): 599-600, June 2002. tab
Artículo
en Inglés
| LILACS
| ID: lil-314530
RESUMO
Neuroschistosomiasis is rarely observed in human pathology, but it is of considerable importance. To investigate its pathogenesis, consequences and response to treatment, an experimental model would be desirable, but is not yet available, in spite of a few indications of a suitable mouse model in the literature. Severe, recent and late Schistosoma mansoni infections in outbred and inbred strains of mice revealed widespread distribution of parasite eggs in several organs, but only exceptionally did eggs reach the encephalus, thus revealing the inadequacy of the mouse as an experimental model for neuroschistosomiasis
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Encéfalo
/
Neuroesquistosomiasis
/
Modelos Animales de Enfermedad
Tipo de estudio:
Estudios de evaluación
Límite:
Animales
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
2002
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Fiocruz/BR
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