Detection of Helicobacter pylori in gastric cancer
Arq. gastroenterol
;
38(4): 240-246, out.-dez. 2001. tab
Artículo
en Inglés
| LILACS
| ID: lil-316288
ABSTRACT
Considering the high prevalence of stomach cancer in the northern region of Brazil and the recognized relationship between chronic gastric inflammation caused by Helicobacter pylori, and its carcinogenic potential, the objective we had with this study was to investigate the presence of the microorganism in macro and microscopic presentations of neoplasm in different regions of the stomach, and in non-malignant lesions concomitant to the adenocarcinoma in patients originating from the metropolitan area of Belem (State of Para, Brazil). METHODS:
Examinations were made on 172 patients divided into two groups group I, formed by 75 patients with gastric carcinoma, and group II, formed by 97 patients with mild enanthematic gastritis, considered control group. The diagnosis was obtained during endoscopic examination and the respective biopsy. Gastric neoplasms were classified macroscopically in accordance with Borrmann's classification, and microscopically in accordance with Lauren's classification. In group I, 54 patients were male and 21 female while in group II, 22 patients were male and 75 female. The average age in group I was 61.2 years (range 27 to 86 years), while in group II it was 37.5 years (range 16 to 69 years). Thin sections were prepared and stained using the hematoxylin-eosin method. In the Helicobacter pylori research, the modified Gram stain was utilized. Statistical analysis was done by utilizing the chi-squared (chi 2) test, Mann-Whitney test (U), and Fisher's exact test.RESULTS:
The results showed the detection of Helicobacter pylori were significantly greater in patients with mild enanthematic gastritis than in patients with gastric carcinoma...
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Índice:
LILACS (Américas)
Asunto principal:
Neoplasias Gástricas
/
Adenocarcinoma
/
Helicobacter pylori
/
Infecciones por Helicobacter
/
Gastritis Atrófica
Tipo de estudio:
Estudio diagnóstico
/
Factores de riesgo
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Arq. gastroenterol
Asunto de la revista:
Gastroenterologia
Año:
2001
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
ABC Medical School/BR
/
Federal University of Pará/BR
/
Hospital do Servidor Público Estadual/BR
/
Instituto de Assistência Médica do Servidor Público/BR
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