Your browser doesn't support javascript.
loading
Influência da elevação sustentada da pressão arterial sobre a dP/dt do ventrículo esquerdo mantendo-se constante a pressão diastólica do ventriículo esquerdo / Influence of Sustained Elevations of Arterial Pressure on the Left Ventricular dP/dt Keeping Constant the Left Ventricular end Diastolic Pressure
Fioretto, Jose Roberto; Okoshi, Katashi; Tucci, Paulo Jose Ferreira.
Afiliación
  • Fioretto, Jose Roberto; Universidade Estadual Paulista (UNESP). Faculdade de Medicina de Botucatu. Departamento de Pediatria. BR
  • Okoshi, Katashi; Universidade Estadual Paulista (UNESP). Faculdade de Medicina de Botucatu. Departamento de Pediatria. BR
  • Tucci, Paulo Jose Ferreira; Universidade Estadual Paulista (UNESP). Faculdade de Medicina de Botucatu. Departamento de Pediatria. BR
Arq. bras. cardiol ; 67(3): 159-164, Set. 1996.
Article en Pt | LILACS | ID: lil-319261
Biblioteca responsable: BR1.1
ABSTRACT

PURPOSE:

To evaluate the influence of sustained elevations of arterial pressure on dP/dt values, while the left ventricular end diastolic pressure was kept constant.

METHODS:

Thirteen anesthetized dogs, mechanically ventilated and submitted to thoracotomy and pharmacological autonomic block (atropine-0.5 mg/kg i.v. + oxprenolol-3 mg/kg i.v.) were studied. The arterial pressure elevation was obtained by mechanical constriction of the descending thoracic aorta. Analyses were made in control (C) situation and after two successive increments of arterial pressure, sustained for 10 min, called hypertension 1 (H1) and hypertension 2 (H2), respectively. The end diastolic left ventricular pressure was kept constant by utilization of a perfusion system connected to the left atria.

RESULTS:

Heart rate did not change (C 125 +/- 13.9 bpm; H1 125 +/- 13.5 bpm; H2 123 +/- 14.1 bpm; p > 0.05); the LVSP increased (C 119 +/- 8.1 mmHg; H1 142 +/- 7.9 mmHg; H2 166 +/- 7.7 mmHg; p < 0.01); the AoDP increased (C 89 +/- 11.6 mmHg; H1 99 +/- 9.5 mmHg; H2 120 +/- 11.8 mmHg; p < 0.01); the LVEDP (C 6.2 +/- 2.48 mmHg; H1 6.3 +/- 2.43 mmHg; H26.1 +/- 2.51 mmHg; p > 0.05) and the dP/dt (C 3068 +/- 1057.1 mmHg/s; H1 3112 +/- 995.7 mmHg/s; H2 3086 +/- 979.5 mmHg/s; p > 0.05) did not change.

CONCLUSION:

dP/dt values are not influenced by a sustained elevation of arterial pressure, when the end diastolic left ventricular pressure is kept constant.
Asunto(s)
Palabras clave
Texto completo: 1 Índice: LILACS Asunto principal: Función Ventricular Izquierda / Presión Arterial / Contracción Miocárdica Límite: Animals Idioma: Pt Revista: Arq. bras. cardiol Asunto de la revista: CARDIOLOGIA Año: 1996 Tipo del documento: Article
Texto completo: 1 Índice: LILACS Asunto principal: Función Ventricular Izquierda / Presión Arterial / Contracción Miocárdica Límite: Animals Idioma: Pt Revista: Arq. bras. cardiol Asunto de la revista: CARDIOLOGIA Año: 1996 Tipo del documento: Article