Toxicidad y neutralización de venenos ofídicos peruanos de los géneros Bothrops y Lachesis (Serpentes: Viperidae) / Toxicity and neutralization of venoms from Peruvian snakes of the genera Bothrops and Lachesis (Serpentes: Viperidae)
Rev. biol. trop
;
41(3A): 351-357, dic. 1993.
Artículo
en Español
| LILACS
| ID: lil-320071
ABSTRACT
The lethal potencies (Median Lethal Dose) of the venoms of Peruvian snakes (Bothrops atrox, Bothrops barnetti, Bothrops pictus and Lachesis muta muta) were determined in mice by using intravenous and intraperitoneal routes of injection. In addition, the neutralizing ability of three antivenoms (bothropic polyvalent, bothropic bivalent and lachetic) was studied by preincubation-type experiments. B. pictus venom had the highest lethality by the intraperitoneal route whereas B. atrox venom had the highest lethality when tested by the intravenous route. The three antivenoms were effective in neutralizing lethality of the homologous venoms. Bivalent antivenom was more effective than polyvalent antivenom in the neutralization of B. pictus venom. On the basis of these findings, the use of bivalent bothropic antivenom is recommended in the Pacific coastal regions of Perú, whereas polyvalent bothropic antivenom is recommended in the oriental jungle regions of the country.
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Índice:
LILACS (Américas)
Asunto principal:
Venenos de Crotálidos
Límite:
Animales
País/Región como asunto:
America del Sur
/
Perú
Idioma:
Español
Revista:
Rev. biol. trop
Asunto de la revista:
Biologia
/
Medicina Tropical
Año:
1993
Tipo del documento:
Artículo
País de afiliación:
Perú
Institución/País de afiliación:
Universidad Pedro Ruiz Gallo/PE
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