Comprometimento da medula óssea e eosinofilia na paracoccidioidomicose / Bone marrow involvement and eosinophilia in paracoccidioidomycosis
Rev. Inst. Med. Trop. Säo Paulo
;
34(2): 85-90, Mar.-Apr. 1992.
Artículo
en Portugués
| LILACS
| ID: lil-320613
RESUMO
The authors described three acute paracoccidioidomycosis patients with bone marrow involvement. P. brasiliensis yeast forms were observed in bone marrow smears of all them, and in one case, culture also revealed fungus growth. The mononuclear phagocytic system involvement, the blood eosinophilia and the negative skin hypersensibility responses were emphasized in all of them, as well as the severity of the disease in one case, with disseminated bone lesions and 20.260 eosinophils/mm3 in peripheral blood. The authors discuss the possible role of eosinophil in the host-parasite interaction in paracoccidioidomycosis, suggesting that TH 2 subpopulation activation and increased IL 5 and GM-CSF secretions may be responsible by eosinophilia in the most severe case.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Paracoccidioidomicosis
/
Médula Ósea
/
Eosinofilia
Límite:
Adolescente
/
Adulto
/
Humanos
Idioma:
Portugués
Revista:
Rev. Inst. Med. Trop. Säo Paulo
Asunto de la revista:
Medicina Tropical
Año:
1992
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade de São Paulo/BR
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