Prognostic factors and relative risk in hypopharyngeal cancer--related parameters concerning stage, therapeutics and evolution
Rev. paul. med
;
111(2): 337-343, Mar.-Apr. 1993.
Artículo
en Inglés
| LILACS
| ID: lil-320833
RESUMO
The prognostic value of 16 parameters was evaluated in a series of 126 squamous cell carcinoma of hypopharynx between 1978 and 1985 at the "Serviço de Cirurgia de Cabeça e Pescoço" of the "Hospital Heliópolis", São Paulo. The variables considered were: age, sex, ethnic background, interval between diagnosis and detection of first symptom, extension of primary lesion (T), N categories, histologic evaluation of primary lesion (pT) and neck node metastasis (pN), number of clinical positive nodes (NGPOS), radiation, chemotherapy and recurrence of the disease (local, regional and distant metastasis). After a multifactorial study using Cox life table model (3) and Dixon mathematic-statistical model (8), 5 of those 16 parameters were found to influence survival, independently. The five variables organized according to hypopharynx cancer prognostic significance were: age, odynophagia, number of clinical (NGPRE) and histological (NGPOS) metastatic lymph nodes and radiation therapy; odynophagia and radiotherapy were the variables that decreased the relative risk of recurrence in the survival of cancer of the hypopharynx.
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Índice:
LILACS (Américas)
Asunto principal:
Carcinoma de Células Escamosas
/
Neoplasias Hipofaríngeas
Tipo de estudio:
Estudio de etiología
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Rev. paul. med
Asunto de la revista:
Medicina
Año:
1993
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Hospital Heliópolis/BR
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