Molecular epidemiology of HIV-1 in Rio Grande, RS, Brazil
Rev. Soc. Bras. Med. Trop
;
35(5): 471-476, Sept.-Oct. 2002. tab
Artículo
en Inglés
| LILACS
| ID: lil-327997
ABSTRACT
We conducted a molecular epidemiological study to investigate HIV-1 strains in Rio Grande, southern Brazil, searching for an association with transmission mode and risk behavior. Patients (185) identified at an AIDS treatment reference Hospital, from 1994 to 1997, were included; from which 107 blood samples were obtained. Nested PCR was realized once for each sample; for amplified samples (69) HIV subtypes were classified using the heteroduplex mobility assay. Subtypes identified were B (75 percent), C (22 percent) and F (3 percent). All infections with C were diagnosed after 1994. Comparing patients with B and C, no differences were detected regarding demographic, clinical and laboratory characteristics; survival analysis did not reveal differences in HIV to AIDS evolution. A higher proportion of injecting drug users, IDU (not significant, p<.07) was found among those with C. This suggests that C may have been introduced in this area through IDU, and is being spread, probably by their sexual partners, to persons with other risk practices
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
ADN Viral
/
Síndrome de Inmunodeficiencia Adquirida
/
VIH-1
Tipo de estudio:
Estudio de etiología
/
Estudio pronóstico
/
Factores de riesgo
/
Estudio de tamizaje
Límite:
Adolescente
/
Adulto
/
Anciano
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Rev. Soc. Bras. Med. Trop
Asunto de la revista:
Medicina Tropical
Año:
2002
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Fundaçäo Universidade Federal do Rio Grande/BR
/
Universidade Federal de Minas Gerais/BR
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