Your browser doesn't support javascript.
loading
Toxicity of puffer fish - two species(Lagocephalus laevigatus, LINAEUS 1766 and Sphoeroides spengleri, BLOCH 1785) from the southeastern Brazilian coast
Oliveira, J. S; Pires Júnior, O. R; Morales, R. A. V; Bloch Júnior, C; Schwartz, C. A; Freitas, J. C.
  • Oliveira, J. S; University of Säo Paulo. Institute of Biosciences and Marine Biology Center. BR
  • Pires Júnior, O. R; University of Brasilia. Department of Physiological Sciences. BR
  • Morales, R. A. V; University of Brasilia. Department of Physiological Sciences. BR
  • Bloch Júnior, C; EMBRAPA. CENARGEN. BR
  • Schwartz, C. A; University of Brasilia. Department of Physiological Sciences. BR
  • Freitas, J. C; University of Säo Paulo. Institute of Biosciences and Marine Biology Center. BR
J. venom. anim. toxins incl. trop. dis ; 9(1): 76-88, 2003. mapas, tab, graf
Artículo en Inglés | LILACS | ID: lil-329533
ABSTRACT
In Brazil, where puffer fish are considered poisonous, there are few documented cases on human consumption and consequent poisoning. In this study, toxicity of two puffer fish species from the Brazilian coast was examined. Specimens of Sphoeroides spengleri and Lagocephalus laevigatus were caught in Säo Sebastiäo Channel (North coast of Säo Paulo State, Brazil) between January 1996 and May 1997. Acidic ethanol extracts from muscle and skin plus viscera were tested for mice acute toxicity using the standard method of Kawabata. Polar extracts of S. spengleri showed high toxicity up to 946 MU/g. Extracts from L. laevigatus showed very low levels of toxicity, never exceeding 1.7 MU/g. All extracts from both species blocked amielinic nerve fiber evoked impulses of crustacean legs; this effect reverted on washing similar to the standard tetrodotoxin TTX. The aqueous extract solutions were partially purified using an ionic exchange column (Amberlit GC-50) followed by treatment with activated charcoal (Norit-A). The presence of TTX and their analogs in the semi-purified extracts were confirmed by HPLC and mass spectrometry (MALDI-TOF).
Asunto(s)
Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Toxinas Biológicas / Brasil / Peces Venenosos / Enfermedades Transmitidas por los Alimentos Límite: Animales País/Región como asunto: America del Sur / Brasil Idioma: Inglés Revista: J. venom. anim. toxins incl. trop. dis Asunto de la revista: Toxicología Año: 2003 Tipo del documento: Artículo País de afiliación: Brasil Institución/País de afiliación: EMBRAPA/BR / University of Brasilia/BR / University of Säo Paulo/BR

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Toxinas Biológicas / Brasil / Peces Venenosos / Enfermedades Transmitidas por los Alimentos Límite: Animales País/Región como asunto: America del Sur / Brasil Idioma: Inglés Revista: J. venom. anim. toxins incl. trop. dis Asunto de la revista: Toxicología Año: 2003 Tipo del documento: Artículo País de afiliación: Brasil Institución/País de afiliación: EMBRAPA/BR / University of Brasilia/BR / University of Säo Paulo/BR