A novel reiterated family of transcribed oligo(A)-terminated, interspersed DNA elements in the genome of Trypanosoma cruzi
Mem. Inst. Oswaldo Cruz
;
98(1): 129-133, Jan. 30, 2003. ilus
Artículo
en Inglés
| LILACS
| ID: lil-331390
ABSTRACT
We report the molecular characterization of a novel reiterated family of transcribed oligo(A)-terminated, interspersed DNA elements in the genome of Trypanosoma cruzi. Steady-state level of transcripts of this sequence family appeared to be developmentally regulated, since only in the replicative forms the parasite showed expression of related sequences with a major band around 3 kb. The presence of frame shifts or premature stop codons predicts that transcripts are not translated. The sequence family also contains truncated forms of retrotransposons elements that may become potential hot spots for retroelement insertion. Sequences homologous to this family are interspersed at many chromosomes including the subtelomeric regions
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Índice:
LILACS (Américas)
Asunto principal:
Trypanosoma cruzi
/
ADN Protozoario
/
Genoma de Protozoos
/
Secuencias Repetitivas Esparcidas
Límite:
Animales
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
2003
Tipo del documento:
Artículo
/
Documento de proyecto
País de afiliación:
Brasil
/
Chile
/
Estados Unidos
/
Venezuela
Institución/País de afiliación:
Escola Paulista de Medicina/BR
/
Northwestern University Medical School/US
/
Universidad Central de Venezuela/VE
/
Universidad de Antofagasta/CL
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