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Estimated prevalence of immunity to poliomyelitis in the city of Säo Paulo, Brazil: a population-based survey
Kiffer, Carlos Roberto Veiga; Conceiçäo, Orlando Jorge; Santos, Edgar Bortholi; Sabino, Ester; Focaccia, Roberto.
  • Kiffer, Carlos Roberto Veiga; University of Säo Paulo. Institute of Infectology Emílio Ribas. Säo Paulo. BR
  • Conceiçäo, Orlando Jorge; University of Säo Paulo. Institute of Infectology Emílio Ribas. Säo Paulo. BR
  • Santos, Edgar Bortholi; University of Säo Paulo. Institute of Infectology Emílio Ribas. Säo Paulo. BR
  • Sabino, Ester; University of Säo Paulo. Institute of Infectology Emílio Ribas. Säo Paulo. BR
  • Focaccia, Roberto; University of Säo Paulo. Institute of Infectology Emílio Ribas. Säo Paulo. BR
Braz. j. infect. dis ; 6(5): 232-243, Oct. 2002. tab, graf
Artículo en Inglés | LILACS, SES-SP | ID: lil-337113
RESUMO

OBJECTIVES:

Estimate the prevalence of immunity to poliomyelitis (anti-polio antibodies) in the city of Säo Paulo/Brazil through a population-based survey.

METHODS:

A quantitative and inductive method was used to draw a representative sample of the population. Randomization and stratification (based on sex, age and residence region) was done, and 1,059 individuals were studied on a home-visit basis (structured questionnaires and blood samples). A microneutralization test was performed to detect anti-polio antibodies against serotypes 1, 2 and 3.

RESULTS:

The estimated prevalence of immunity to poliomyelitis was high, with 94.6 percent prevalence of anti-polio 1 antibodies, 98.8 percent anti-polio 2 and 91.9 percent anti-polio 3. Despite this high prevalence, there were significantly lower prevalence levels in some groups, specially among age and residence region groups.

DISCUSSION:

Routine child immunization and NIDs with OPV have provided excellent levels of serological immunity to poliomyelitis in the population of the city of Säo Paulo, Brazil. However, there may be specific groups with a lower prevalence of immunity. Estimations of the prevalence of immunity to poliomyelitis were made in a population-based survey, which could be used as an auxiliary tool for supporting the polio eradication program
Asunto(s)
Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Poliomielitis / Poliovirus / Anticuerpos Antivirales Tipo de estudio: Ensayo Clínico Controlado / Estudio de prevalencia / Investigación cualitativa / Factores de riesgo / Estudio de tamizaje Límite: Adolescente / Adulto / Niño / Child, preschool / Femenino / Humanos / Masculino País/Región como asunto: America del Sur / Brasil Idioma: Inglés Revista: Braz. j. infect. dis Año: 2002 Tipo del documento: Artículo Institución/País de afiliación: University of Säo Paulo/BR

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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Poliomielitis / Poliovirus / Anticuerpos Antivirales Tipo de estudio: Ensayo Clínico Controlado / Estudio de prevalencia / Investigación cualitativa / Factores de riesgo / Estudio de tamizaje Límite: Adolescente / Adulto / Niño / Child, preschool / Femenino / Humanos / Masculino País/Región como asunto: America del Sur / Brasil Idioma: Inglés Revista: Braz. j. infect. dis Año: 2002 Tipo del documento: Artículo Institución/País de afiliación: University of Säo Paulo/BR