The influence of periportal (pipestem) fibrosis on long term results of surgical treatment for schistosomotic portal hypertension
Arq. gastroenterol
;
40(1): 4-10, Jan.-Mar. 2003. ilus, tab
Artículo
en Inglés
| LILACS
| ID: lil-347604
ABSTRACT
AIM:
To evaluate the degree of influence that periportal fibrosis has on clinical development and the long term results of surgical treatment on patients with hepatic-splenic schistosomiasis with previous gastrointestinal hemorrhages.METHODS:
During the period of 1992-1998, 111 patients underwent surgical treatment for the treatment of hepatic-splenic schistosomiasis with previous gastrointestinal hemorrhages. The degree of fibrosis was classified as degree I - the portal spaces show a rich increase of young connective cells, a slight collagen production and a varying presence of inflammatory infiltrate. The periportal blade unchangeable (29/111); degree II - there is an expansion of the connective tissue with the emission of radial collagen septa, producing a star shaped aspect (38/111); degree III - the connective septa form bridges with other portal spaces or with the vein, with evident angiomatoid neo-formation (44/111).CONCLUSION:
The patients with periportal fibrosis degree I present recurrent hemorrhages statistically less than patients with periportal fibrosis degrees II and III, and that the intensity of the periportal fibrosis is not the only pathophysiological factor of the esophageal varices, gastric varices, prevalence of post-operative portal vein thrombosis and hematological and biochemical alterations of the patients with pure mansoni schistosomiasis.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Vena Porta
/
Esquistosomiasis mansoni
/
Hemorragia Gastrointestinal
/
Hipertensión Portal
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Arq. gastroenterol
Asunto de la revista:
Gastroenterologia
Año:
2003
Tipo del documento:
Artículo
/
Congreso y conferencia
País de afiliación:
Brasil
Institución/País de afiliación:
Federal University of Pernambuco/BR
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