Malformaciones congénitas y patología crónica de la madre: estudio ECLAMC 1971-1999 / Association between congenital malformations and chronic diseases of the mother
Rev. méd. Chile
;
131(4): 404-411, abr. 2003. tab
Artículo
en Español
| LILACS
| ID: lil-348368
RESUMO
Background:
Several maternal diseases, such as diabetes mellitus or high blood pressure, are associated with a higher risk for fetal or neonatal problems.Aim:
To study the association between chronic diseases of the mother and congenital malformations. Material andmethods:
Review of the records of the Latin American Collaborative Study of Congenital Malformations (ECLAMC) at the University of Chile Clinical Hospital. A sample of 383 mothers with a chronic disease was compared with 297 healthy mothers. The presence of congenital malformations in the newborns was studied. The odds ratio (OR) of a mother to have a child with a congenital malformation was calculated.Results:
Mothers with bronchial asthma, diabetes mellitus, hypertension and hypothyroidism had an OR over 1 of having a child with a congenital malformation. No association between maternal obesity and offspring malformations was observed. Offspring of diabetic mothers had 8.95 times more probabilities of having a major malformation and 4.95 times more probabilities of having a minor defect.Conclusions:
Offspring of mothers with diabetes mellitus, bronchial asthma, hypertension or hypothyroidism have a higher risk of presenting a congenital malformation, when compared with offspring of healthy mothers
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Anomalías Congénitas
/
Embarazo de Alto Riesgo
/
Intercambio Materno-Fetal
Tipo de estudio:
Factores de riesgo
Límite:
Femenino
/
Humanos
/
Recién Nacido
/
Embarazo
Idioma:
Español
Revista:
Rev. méd. Chile
Asunto de la revista:
Medicina
Año:
2003
Tipo del documento:
Artículo
País de afiliación:
Chile
Institución/País de afiliación:
Universidad de Chile/CL
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