Antimicrobial activity in vitro of plumbagin isolated from Plumbago species
Mem. Inst. Oswaldo Cruz
;
98(7): 959-961, Oct. 2003. ilus, tab
Artículo
en Inglés
| LILACS
| ID: lil-352401
RESUMO
Plumbagin is a naturally occurring naphthoquinone isolated from roots of Plumbago scandens. The plant was collected at the Campus of Fundação Oswaldo Cruz, Rio de Janeiro, Brazil. P. scandens is used as a traditional medicine for the treatment of several diseases. The antimicrobial activity of plumbagin was evaluated using the macrodilution method. The compound exhibited relatively specific activity against bacteria and yeast. The minimum inhibitory concentration test showed the growth inhibiton of Staphylococcus aureus at a concentration of 1.56 æg/ml and of Candida albicans at a concentration of 0.78 æg/ml. These results suggest the naphthoquinone plumbagin as a promising antimicrobial agent.
Texto completo:
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Índice:
LILACS (Américas)
Asunto principal:
Salmonella typhimurium
/
Staphylococcus aureus
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Candida albicans
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Plumbago litteralis
/
Escherichia coli
/
Antiinfecciosos
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
2003
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Fiocruz/BR
/
Universidade Federal do Rio de Janeiro/BR
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