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Angiogenesis and cancer: recent advances
Cáceres, W; González, S.
  • Cáceres, W; San Juan Veterans Affairs Medical Center. San Juan. PR
  • González, S; s.af
P. R. health sci. j ; 22(2): 149-151, June 2003.
Artículo en Inglés | LILACS | ID: lil-356188
RESUMO
Recent studies have shown the possibility to treat cancer with drugs that affect the formation of new blood vessels instead of attacking directly the malignant cell. This relatively new field in the area of oncology on angiogenesis inhibition has expanded the therapeutic option for malignant diseases. We will discuss several antiangiogenesis drugs in clinical development and their mechanism of action. Some of these drugs include angiostatin, metalloproteinase inhibitors, thalidomide, tamoxifen, interferons and others. The use of antiangiogenic agents, both in combination with other treatment modalities in the acute setting as well as long-term maintenance or prevention of cancer, is at present one of the better promises in the war against cancer.
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Índice: LILACS (Américas) Asunto principal: Inhibidores de la Angiogénesis / Neoplasias / Neovascularización Patológica Límite: Humanos Idioma: Inglés Revista: P. R. health sci. j Asunto de la revista: Medicina Año: 2003 Tipo del documento: Artículo País de afiliación: Puerto Rico Institución/País de afiliación: San Juan Veterans Affairs Medical Center/PR

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Índice: LILACS (Américas) Asunto principal: Inhibidores de la Angiogénesis / Neoplasias / Neovascularización Patológica Límite: Humanos Idioma: Inglés Revista: P. R. health sci. j Asunto de la revista: Medicina Año: 2003 Tipo del documento: Artículo País de afiliación: Puerto Rico Institución/País de afiliación: San Juan Veterans Affairs Medical Center/PR