Exposición a pesticidas y toxicidad reproductiva y del desarrollo en humanos: análisis de la evidencia epidemiológica y experimental / Pesticide exposure and reproductive and birth defects: critical analysis of epidemiological and experimental evidence
Rev. méd. Chile
;
132(7): 873-879, jul. 2004. tab
Artículo
en Español
| LILACS
| ID: lil-366590
ABSTRACT
Several epidemiological studies link pesticide exposure to reproductive and developmental toxicity. However, additional studies have shown little or no evidence to support such relationship. On the other hand, experimental data show that some pesticides may indeed alter the reproductive function or produce birth defects (as evidenced by intrauterine death, in utero growth retardation, visceral and skeletal malformations or functional deficits) in laboratory animals. This review is a critical analysis of the epidemiological and experimental evidence available to date, that links pesticide exposure with induction of reproductive or developmental defects. Factors that must be considered when establishing a cause-effect relationship are also discussed, including the shape of the dose-response curve, exposure to pesticides in chemical mixtures and the influence of genetic background.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Plaguicidas
/
Exposición Profesional
/
Enfermedades de los Trabajadores Agrícolas
Límite:
Animales
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Chile
Idioma:
Español
Revista:
Rev. méd. Chile
Asunto de la revista:
Medicina
Año:
2004
Tipo del documento:
Artículo
/
Documento de proyecto
País de afiliación:
Chile
Institución/País de afiliación:
Universidad de Valparaíso/CL
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