Red cell glutathione reductase saturation obtained with oral riboflavin supplementation
Rev. Inst. Adolfo Lutz
; 62(2): 91-94, 2003. tab, graf
Article
en En
| LILACS, SES-SP
| ID: lil-383427
Biblioteca responsable:
BR91.2
RESUMO
The erythrocyte glutathione reductase (E-GR) saturation with its coenzyme flavin adenine dinucleotide (FAD) affords the nutritional status regarding the vitamin B2, as FAD proceeds from riboflavin intake. E-GR normally exhibits physiological partial saturation with its coenzyme. OBJECTIVE:
To study the maximum in vivo saturation which could be reached by increasingly oral vitamin supplemetantion.METHODS:
Three groups of normal volunteers were given 3 mg (group A), 20 mg ( group B) and 50 mg (group C) riboflavin daily during twenty days. The enzyme activities were assayed before and after supplementation, with and without coenzyme addition to the reagent system.RESULTS:
77 per cent, 83 per cent and 87 per cent saturation were observed in the groups A, B and C respectively.CONCLUSION:
Increasing in vivo saturation was observed with increasing oral doses of riboflavin supplementation, but total saturation was not observed even with the highest oral 50 mg roboflavin supplementation
Texto completo:
1
Índice:
LILACS
Asunto principal:
Riboflavina
/
Eritrocitos
/
Glutatión
Idioma:
En
Revista:
Rev. Inst. Adolfo Lutz
Asunto de la revista:
MICROBIOLOGIA
/
SAUDE PUBLICA
Año:
2003
Tipo del documento:
Article