Avidity of IgG for rubella: an evaluation of the need for implementation at the Materno-Infantil Presidente Vargas Hospital in Porto Alegre, Rio Grande do Sul, Brazil
Braz. j. infect. dis
;
8(3): 249-254, Jun. 2004. tab
Artículo
en Inglés
| LILACS
| ID: lil-384164
ABSTRACT
Rubella serum assays performed in the laboratory of the Materno-Infantil Presidente Vargas Hospital (HMIPV) from 1998 to 2002 were reviewed to determine if IgG avidity assays should be implemented. IgG was determined using the Enzyme Linked Fluorescent Assay, ELFA, VIDAS® system, bioMérieux or the Microparticle Enzyme Immunoassay, MEIA, Axsym® system, Abbott, and IgM was determined using the ELFA, VIDAS® system, bioMérieux, a capture format assay. Specific IgG was assayed in 2,863 samples, with positive results for 84 percent of the patients, for the most part with high levels of antibodies. IgM was assayed in 2,851 samples, being positive in 14 (0.49 percent) and inconclusive in 25 (0.88 percent). Serology for toxoplasmosis was also positive or inconclusive in 5 patients. After a cost-effectiveness analysis, it was decided not to implement avidity assays, considering that the HMIPV is a public institution, with limited funding. Difficulties concerning the integration of the Clinical Pathology Service with the Clinical Staff of the institution were also considered.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Rubéola (Sarampión Alemán)
/
Virus de la Rubéola
/
Inmunoglobulina G
/
Inmunoglobulina M
/
Anticuerpos Antivirales
/
Afinidad de Anticuerpos
Límite:
Adolescente
/
Adulto
/
Niño
/
Child, preschool
/
Femenino
/
Humanos
/
Lactante
/
Embarazo
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Braz. j. infect. dis
Asunto de la revista:
Enfermedades Transmisibles
Año:
2004
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Fundação Faculdade Federal de Ciências Médicas de Porto Alegre/BR
/
Hospital Materno Infantil Presidente Vargas/BR
/
Universidade Luterana do Brasil/BR
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