Intestinal parasitic infections and eosinophilia in an human immunedeficiency virus positive population in Honduras
Mem. Inst. Oswaldo Cruz
;
99(7): 773-778, Nov. 2004. tab
Artículo
en Inglés
| LILACS
| ID: lil-391611
RESUMO
The occurrence of intestinal parasites, their regional distribution and their relations to eosinophilia were studied in 133 human immunodeficiency virus (HIV) positive individuals from Honduras. After signing an informed consent, participants answered a socio-demographic and risk factor questionnaire, a complete physical examination, medical history, and a series of laboratory tests. All participants were HIV positive but not acquired immunodeficiency syndrome positive. Of them, 67 percent were co-infected with pathogen and non pathogen parasites. Overall occurrence of nematodes was 44.3 percent for Trichuris trichiura, 24 percent for Ascaris lumbricoides, 12 percent for Hookworm and 7.5 percent for Strongyloides stercoralis. No cases of Giardia lamblia, acute amebiasis or cryptosporidiasis were diagnosed. Mean eosinophil percents for participants were consistently and significantly higher in infected than in non infected individuals 22 percent for Hookworm vs 7.2 percent (p < 0.001), 11 percent for Trichuris compared to 5.2 percent (p < 0.001), 13.2 percent compared to 7.5 percent for S. stercoralis (p < 0.05), and 12 percent compared to 6 percent for Ascaris cases (p < 0.05). Helminths and non pathogenic protozoa, as single or mixed infections, occurred among the participants. There was a strong correlation between eosinophilia and helminthiasis infections; however, none was identified between CD4 levels and eosinophilia. Because parasitic infections aggravate malnutrition and promote a disbalanced Th2 response in a potentially immuno-compromised host, their effect on HIV disease progression needs further study, mainly in countries were HIV and parasitic infections are highly prevalent.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Seropositividad para VIH
/
Eosinofilia
/
Parasitosis Intestinales
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Estudio de prevalencia
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Animales
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America Central
/
Honduras
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
2004
Tipo del documento:
Artículo
País de afiliación:
Honduras
/
Estados Unidos
Institución/País de afiliación:
Florida International University/US
/
Universidad Nacional Autónoma de Honduras/HN
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