Local anaesthetic medication for the treatment of asthma
Mem. Inst. Oswaldo Cruz
;
100(supl.1): 161-165, Mar. 2005.
Artículo
en Inglés
| LILACS
| ID: lil-402193
RESUMO
It is presumed that drugs able to prevent bronchial spasm and/or inflammation may have therapeutic potential to control asthma symptoms. The local anaesthetic lidocaine has recently received increased attention as an alternative form of treatment for asthmatic patients. This paper reviews the major findings on the topic and summarizes the putative mechanisms underlying the airway effects of local anaesthetic agents. We think that lidocaine extends the spectrum of options in asthma therapy, probably by counteracting both spasmogenic and inflammatory stimuli in the bronchial airways. The possibility of development of new anti-asthma compounds based on the synthesis of lidocaine derivatives is also on the horizon.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Asma
/
Antiasmáticos
/
Anestésicos Locales
/
Lidocaína
Límite:
Humanos
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
2005
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Instituto Oswaldo Cruz/BR
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