A mucin like gene different from the previously reported members of the mucin like gene families is transcribed in Trypanosoma cruzi but not in Trypanosoma rangeli
Mem. Inst. Oswaldo Cruz
;
100(4): 391-395, July 2005. ilus
Artículo
en Inglés
| LILACS
| ID: lil-405994
ABSTRACT
Trypanosoma cruzi expresses mucin like glycoproteins encoded by a complex multigene family. In this work, we report the transcription in T. cruzi but not in T. rangeli of a mucin type gene automatically annotated by the T. cruzi genome project. The gene showed no nucleotide similarities with the previously reported T. cruzi mucin like genes, although the computational analysis of the deduced protein showed that it has the characteristic features of mucins a signal peptide sequence, O-glycosylation sites, and glycosylphosphatidylinositol (GPI) anchor sequence. The presence in this gene of N- terminal and C- terminal coding sequences common to other annotated mucin like genes suggests the existence of a new mucin like gene family.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Trypanosoma cruzi
/
Genes Protozoarios
/
Mucinas
Límite:
Animales
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
2005
Tipo del documento:
Artículo
/
Documento de proyecto
País de afiliación:
Cuba
/
Venezuela
Institución/País de afiliación:
Instituto de Medicina Tropical Dr Félix Pifano/VE
/
Universidad Central de Venezuela/VE
/
Universidad Simón Bolívar/VE
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