In vitro anti-proliferation/cytotoxic activity of sixty natural products on the human SH-SY5Y neuroblastoma cells with specific reference to dibenzyl trisulphide
West Indian med. j
;
53(4): 208-219, Sept. 2004.
Artículo
en Inglés
| LILACS
| ID: lil-410433
RESUMO
Sixty natural products belonging to the following structural classes artemisinins, coumarins, flavonoids, tannins, tetrahydroberberine alkaloids, tetracyclic triterpenes, tetranortriterpenoids and polysulphides were screened against the human SH-SY5Y neuroblastoma cell line revealing differences in their effects on cell morphology and in anti-proliferation/cytotoxic activity. Based on the data obtained, dibenzyl trisulphide is the most effective anti-proliferative/cytotoxic compound. In addition, we hereby propose the human SH-SY5Y cell line as a sensitive and uncomplicated in vitro test system for detecting compounds with potential anti-proliferation/cytotoxic activity
Buscar en Google
Índice:
LILACS (Américas)
Asunto principal:
Sulfuros
/
Compuestos de Bencilo
/
Extractos Vegetales
/
Neuroblastoma
/
Antineoplásicos
Límite:
Humanos
Idioma:
Inglés
Revista:
West Indian med. j
Asunto de la revista:
Medicina
Año:
2004
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS