Leiomyosarcoma of the rectum. A report of two cases and review of the literature
West Indian med. j
;
53(2): 122-125, Mar. 2004.
Artículo
en Inglés
| LILACS
| ID: lil-410523
RESUMO
Rectal leiomyosarcoma is rare. It is frequently treated by abdominoperineal resection. The role of adjuvant therapy is unclear. Two cases of rectal leiomyosarcoma are presented. Pre-operative endorectal ultrasound predicted submucosal invasion in one case treated by low restorative resection and muscularis propria infiltration in the other managed with abdominoperineal resection. In both cases, ultrasound suggested malignant characteristics as evident by heterogeneous cystic spaces, irregular outline, large size and echogenic foci. Histology was CD34 negative and desmin, alpha-smooth muscle actin and HHF-35 positive, distinguishing these tumours from gastrointestinal stromal tumours. Rectal leiomyosarcoma may be successfully treated by restorative resection and pre-operative ultrasound is useful in assisting this surgical decision by defining malignant features of the tumour. Histopathological characteristics predictive of poor prognosis include high mitotic activity, intratumoural necrosis and tumour size
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Índice:
LILACS (Américas)
Asunto principal:
Neoplasias del Recto
/
Leiomiosarcoma
Tipo de estudio:
Estudio pronóstico
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
West Indian med. j
Asunto de la revista:
Medicina
Año:
2004
Tipo del documento:
Artículo
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