A follow up study of cytomegalovirus infection in a group of Turkish renal transplant recipients using molecular assays
Mem. Inst. Oswaldo Cruz
;
100(3): 263-267, May 2005. tab
Artículo
en Inglés
| LILACS
| ID: lil-411021
ABSTRACT
The clinical value of an in-house cytomegalovirus nested polymerase chain reaction (CMV-PCR) and a commercial molecular assay hybrid capture CMV DNA assay (HCA) was evaluated in monitoring a group of renal transplant patients for six months follow up. In this study, the sensitivity, specificity, positive predictive value, and negative predictive value of nested CMV DNA PCR assay and HCA at the beginning of the study were 70, 42.9, 46.7, 66.7, and 60, 78.6, 66.7, and 73.3 percent respectively. After six months, they were 80, 66.7, 80, 66.7 for CMV PCR and 73.3, 88.9, 91.7, 66.7 percent for HCA respectively. These results indicate that in monitoring and predicting CMV infections in renal transplant recipients, not only qualitative but also quantitative assays must be used together in order to decide the preemptive strategies.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Trasplante de Riñón
/
Infecciones por Citomegalovirus
/
Citomegalovirus
/
Leucocitos
Tipo de estudio:
Estudio diagnóstico
/
Estudios de evaluación
/
Estudio observacional
/
Estudio pronóstico
/
Investigación cualitativa
/
Factores de riesgo
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
2005
Tipo del documento:
Artículo
/
Documento de proyecto
País de afiliación:
Turquía
Institución/País de afiliación:
Gazi University/TR
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