Study on the susceptibility of Enterococcus faecalis from infectious processes to ciprofloxacin and vancomycin
J. venom. anim. toxins incl. trop. dis
;
11(3): 252-260, jul.-set. 2005. tab
Artículo
en Inglés
| LILACS
| ID: lil-414924
ABSTRACT
Enterococcus faecalis is considered a pathogen responsible for hospital infections and, due to its frequent multi-resistant profile, has caused preoccupations among many medical authorities. The objective of this study was to determine the antimicrobial susceptibility of 74 strains isolated from blood cultures and purulent secretions to vancomycin and ciprofloxacin through the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) by using the Microdilution test. The results showed a greater efficacy of vancomycin compared to ciprofloxacin (98.6% of the strains were inhibited by vancomycin at lower concentrations 0.06 - 1 mg/ml). However, in the MBC analysis 73% of the strains showed a MBC of vancomycin only at high concentrations (equal to or higher than 64 mg/ml). For ciprofloxacin, the strains showed a broad sensitivity with MICs and MBCs distributed along all the MIC classes. Results also revealed a probability that some strains are tolerant to vancomycin, which indicates the need of other tests to confirm this characteristic
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Infecciones Bacterianas
/
Vancomicina
/
Ciprofloxacina
/
Enterococcus faecalis
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
J. venom. anim. toxins incl. trop. dis
Asunto de la revista:
Toxicología
Año:
2005
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Sao Paulo State University/BR
Similares
MEDLINE
...
LILACS
LIS