Prediction of hybrid means from a partial circulant diallel table using the ordinary least square and the mixed model methods
Genet. mol. biol
; 28(2): 314-320, 2005. tab
Article
en En
| LILACS
| ID: lil-416304
Biblioteca responsable:
BR1.1
RESUMO
By definition, the genetic effects obtained from a circulant diallel table are random. However, because of the methods of analysis, those effects have been considered as fixed. Two different statistical approaches were applied. One assumed the model to be fixed and obtained solutions through the ordinary least square (OLS) method. The other assumed a mixed model and estimated the fixed effects (BLUE) by generalized least squares (GLS) and the best linear unbiased predictor (BLUP) of the random effects. The goal of this study was to evaluate the consequences when considering these effects as fixed or random, using the coefficient of correlation between the responses of observed and non-observed hybrids. Crossings were made between S1 inbred lines from two maize populations developed at Universidade Federal de Goiás, the UFG-Samambaia "Dent" and UFG-Samambaia "Flint". A circulant inter-group design was applied, and there were five (s = 5) crossings for each parent. The predictions were made using a reduced model. Diallels with different sizes of s (from 2 to 5) were simulated, and the coefficients of correlation were obtained using two different approaches for each size of s. In the first approach, the observed hybrids were included in both the estimation of the genetic parameters and the coefficient of correlation, while in the second a cross-validation process was employed. In this process, the set of hybrids was divided in two groups one group, comprising 75 percent of the original group, to estimate the genetic parameters, and a second one, consisting of the remaining 25 percent, to validate the predictions. In all cases, a bootstrap process with 200 resamplings was used to generate the empirical distribution of the correlation coefficient. This coefficient showed a decrease as the value of s decreased. The cross-validation method allowed to estimate the bias magnitude in evaluating the correlation coefficient using the same hybrids, to predict the genetic parameters and the correlation evaluation. The bias was shown to be greater when the OLS method was used...
Texto completo:
1
Índice:
LILACS
Asunto principal:
Zea mays
/
Modelos Genéticos
Tipo de estudio:
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Genet. mol. biol
Asunto de la revista:
GENETICA
Año:
2005
Tipo del documento:
Article