Use of Cavia porcellus (Guinea Pigs) as an experimental model for Leishmania (Viannia) braziliensis
J. venom. anim. toxins incl. trop. dis
; 11(4): 605-609, out.-dez. 2005.
Article
en En
| LILACS
| ID: lil-417730
Biblioteca responsable:
BR33.1
RESUMO
Laboratory animals are fundamental to study immunological aspects and the efficacy of new drugs to treat leishmaniasis. However, we do not have practical and good animal models to study leishmaniasis caused by Leishmania (Viannia) braziliensis - L(V)b. In this study, thirty-two experimental animals (Cavia porcellus) were injected in the hind foot with 3x105 promastigote forms of L(V)b. The animals were followed for eight weeks. None of the experimental animals developed lesions or presented the parasite in any of the tests performed (histopathological exam, smears, culture, inoculation in hamsters, and polymerase chain reaction)
Texto completo:
1
Índice:
LILACS
Asunto principal:
Leishmania braziliensis
/
Cobayas
Límite:
Animals
País/Región como asunto:
America do sul
/
Brasil
Idioma:
En
Revista:
J. venom. anim. toxins incl. trop. dis
Asunto de la revista:
TOXICOLOGIA
Año:
2005
Tipo del documento:
Article