Effect of the essential oil of Achillea millefolium L. in the production of hydrogen peroxide and tumor necrosis factor-"ALPHA" in murine macrophages
RBCF, Rev. bras. ciênc. farm. (Impr.)
;
41(3): 401-405, jul.-set.2005. tab, graf
Artículo
en Inglés
| LILACS
| ID: lil-427936
RESUMO
Macrophages release more than one hundred compounds into the extracellular environment. Among these, there are cytokines and intermediate oxigen compounds, such as TNF-"ALPHA" and 'H POT. 2''O POT. 2'. We evaluated the effect of the crude essential oil of Achillea millefolium L. (Asteraceae) by determining hydrogen peroxide ('H POT. 2''O POT. 2') and tumor necrosis factor-a (TNF-"ALPHA") release in cultures of peritoneal macrophages cells from Swiss mice. Commercial azulene was also tested for comparison with the essential oil. The macrophages viability in the presence of the oil was analyzed and dilutions of 1100 and 1200 showed the best results. A mild production of 'H POT. 2''O POT. 2' and a moderate liberation of TNF-"ALPHA" were observed...
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Aceites Volátiles
/
Millefolium
/
Factor de Necrosis Tumoral alfa
/
Macrófagos Peritoneales
/
Peróxido de Hidrógeno
Límite:
Animales
Idioma:
Inglés
Revista:
RBCF, Rev. bras. ciênc. farm. (Impr.)
Asunto de la revista:
Bioquímica
/
Farmacia
/
Farmacología
Año:
2005
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Estadual Paulista/BR
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