Susceptibilidad in vitro de bacterias anaeróbicas en infecciones pleuropulmonares / In vitro antimicrobial susceptibility of anaerobic bacteria isolated from pleuropulmonary infections
Rev. méd. Chile
;
134(4): 465-468, abr. 2006. tab
Artículo
en Español
| LILACS
| ID: lil-428546
RESUMO
Background:
Aspirative pleuropulmonary infections are usually caused by anaerobic flora of the mouth, mainly Prevotella, Fusobacterium and Peptostreptococcus spp. Penicillin in high doses is the traditional treatment for this type of infections but the rising resistance developed in recent years has induced the empiric use of clindamycin, increasing treatment costs.Aim:
To study antimicrobial susceptibility of anaerobic bacteria isolated from pleuropulmonary infections. Material andmethods:
Thirty two strains obtained from bronchoalveolar lavage and 15 strains isolated from pleural effusions between 2000 and 2002, were studied. The phenotype of strains was identified using the semiautomated API 20 A method and their susceptibility to penicillin (PNC), clindamycin (CM) and chloramphenicol (CAF) was tested using the E test methods.Results:
All the strains were susceptible to CAF, 95% to CM and 74.4% to PNC. The predominant genus was Prevotella, which also exhibited the higher resistance.Conclusions:
As CM and CAF are active "in vitro", high rates of clinical response should be expected. In contrast, PNC is less effective, especially against pigmented Prevotella.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Bacterias Anaerobias
/
Infecciones Bacterianas
/
Neumonía Bacteriana
/
Farmacorresistencia Bacteriana Múltiple
/
Antibacterianos
Límite:
Humanos
Idioma:
Español
Revista:
Rev. méd. Chile
Asunto de la revista:
Medicina
Año:
2006
Tipo del documento:
Artículo
País de afiliación:
Chile
Institución/País de afiliación:
Instituto Nacional del Tórax/CL
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