Amiloidosis, Comunicación de 11 casos y revisión de la literatura / Clinical features of patients with the pathological diagnosis of amyloidosis
Rev. méd. Chile
; 133(6): 655-661, jun. 2005. ilus, tab
Article
en Es
| LILACS
| ID: lil-429119
Biblioteca responsable:
BR1.1
RESUMO
Background:
Amyloidosis is characterized by the extracellular deposit of an insoluble fibrillar protein that leads to tissue atrophy and necrosis.Aim:
To report the clinical features of cases of amyloidosis diagnosed in a public hospital in Santiago, Chile, from 2000 to 2004. Material andmethods:
Retrospective review of all pathology reports of biopsies obtained from 2000 to 2004. In all cases reported as "amyloidosis", the clinical features of such patients were obtained from their medical records.Results:
The medical records of 11 patients with amyloidosis were obtained (aged 35 to 71 year old, seven females). Seven had a systemic and four a localized disease. Six patients had primary amyloidosis and in one, it was secondary to a disseminated tuberculosis. Five patients with the generalized disease consulted for anarsarca, three for weight loss and 2 for chronic diarrhea. Patients with localized disease consulted for tonsil enlargement, dysphonia and skin lesions. Five patients with generalized disease had renal involvement and five had cardiac involvement. Three patients had malabsorption.Conclusions:
The most common presentation of systemic amyloidosis is anasarca and renal involvement is common.
Texto completo:
1
Índice:
LILACS
Asunto principal:
Enfermedades de la Piel
/
Amiloidosis
/
Enfermedades Renales
/
Hepatopatías
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
Idioma:
Es
Revista:
Rev. méd. Chile
Asunto de la revista:
MEDICINA
Año:
2005
Tipo del documento:
Article