Frequency of serovars and antimicrobial resistance in Shigella spp. from Brazil
Mem. Inst. Oswaldo Cruz
;
101(3): 245-250, May 2006. tab
Artículo
en Inglés
| LILACS
| ID: lil-431720
RESUMO
A total of 296 Shigella spp. were received from State Public Health Laboratories, during the period from 1999 to 2004, by National Reference Laboratory for Cholera and Enteric Diseases (NRLCED) - IOC/Fiocruz, Rio de Janeiro, Brazil. The frequency of Shigella spp. was S. flexneri (52.7 percent), S. sonnei (44.2 percent), S. boydii (2.3 percent), and S. dysenteriae (0.6 percent). The most frequent S. flexneri serovars were 2a and 1b. The highest incidence rates of Shigella isolation were observed in the Southeast (39 percent) and Northeast (34 percent) regions and the lowest rate in the South (3 percent) of Brazil. Strains were further analyzed for antimicrobial susceptibility by disk diffusion method as part of a surveillance program on antimicrobial resistance. The highest rates of antimicrobial resistance were to trimethoprim-sulfamethozaxole (90 percent), tetracycline (88 percent), ampicillin (56 percent), and chloramphenicol (35 percent). The patterns of antimicrobial resistance among Shigella isolates pose a major difficulty in the determination of an appropriate drug for shigellosis treatment. Continuous monitoring of antimicrobial susceptibilities of Shigella spp. through a surveillance system is thus essential for effective therapy and control measures against shigellosis.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Shigella
/
Antibacterianos
Tipo de estudio:
Estudio de prevalencia
/
Factores de riesgo
Límite:
Humanos
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
2006
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Fundação Oswaldo Cruz/BR
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