Stereological study of collagen and elastic system in the detrusor muscle of bladders from controls and patients with infravesical obstruction
Int. braz. j. urol
; 33(1): 33-41, Jan.-Feb. 2007. ilus, tab
Article
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| LILACS
| ID: lil-447464
Biblioteca responsable:
BR1.1
ABSTRACT
OBJECTIVE:
Compare detrusor muscle of normal and patients with infravesical obstruction, quantifying the collagen and elastic system fibers. MATERIALS ANDMETHODS:
We studied samples taken from bladders of 10 patients whose ages ranged from 45 to 75 years (mean = 60 years), who underwent transvesical prostatectomy for treatment of BPH. Control material was composed of 10 vesical specimens, removed during autopsies performed in cadavers of accident victims, with ages between 18 and 35 years (mean = 26 years).RESULTS:
The results of collagen and elastic fibers quantification (volumetric density) demonstrated the following results in percentage (mean +/- standard deviation) collagen in BPH patients = 4.89 +/- 2.64 and 2.32 +/- 1.25 in controls (p < 0.0001), elastin in BPH patients = 10.63 percent +/- 2.00 and 8.94 percent +/- 1.19 in controls (p < 0.0001).CONCLUSION:
We found that the components of connective tissue, collagen and elastic system fibers are increased in the detrusor muscle of patients with infravesical obstruction, when compared to controls.Palabras clave
Texto completo:
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Índice:
LILACS
Asunto principal:
Hiperplasia Prostática
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Obstrucción del Cuello de la Vejiga Urinaria
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Colágeno
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Tejido Elástico
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Hipertonía Muscular
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Músculo Liso
Tipo de estudio:
Observational_studies
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Risk_factors_studies
Límite:
Adolescent
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Adult
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Humans
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Male
Idioma:
En
Revista:
Int. braz. j. urol
Asunto de la revista:
UROLOGIA
Año:
2007
Tipo del documento:
Article