The time has come: a new scene for PKU treatment
Genet. mol. res. (Online)
;
5(1): 33-44, Mar. 31, 2006. tab, ilus
Artículo
en Inglés
| LILACS
| ID: lil-449148
ABSTRACT
Phenylketonuria (PKU) is one of the few genetic diseases in which mental retardation can be prevented. Hence, diagnosis and treatment must be established early. PKU treatment consists of a phenylalanine-restricted diet supplemented with a phenylalanine-free mixture of amino acids. However, it is difficult to adhere to this diet. In the last decade, a better comprehension of the biochemistry, genetics and molecular basis of the disease, as well as the need for easier treatment, led to the development of several new therapeutic strategies for PKU. In the present study, we evaluated these new therapeutic options in terms of theoretical basis, methodologies, efficacy, and costs.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Fenilalanina Hidroxilasa
/
Fenilcetonurias
/
Alimentos Formulados
/
Dieta con Restricción de Proteínas
Límite:
Humanos
Idioma:
Inglés
Revista:
Genet. mol. res. (Online)
Asunto de la revista:
Biologia Molecular
/
Genética
Año:
2006
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Federal de Minas Gerais/BR
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