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Pathology and pathophysiology of pulmonary manifestations in leptospirosis
Dolhnikoff, Marisa; Mauad, Thais; Bethlem, Eduardo P; Carvalho, Carlos Roberto Ribeiro.
  • Dolhnikoff, Marisa; University of São Paulo. School of Medicine. Department of Pathology. São Paulo. BR
  • Mauad, Thais; University of São Paulo. School of Medicine. Department of Pathology. São Paulo. BR
  • Bethlem, Eduardo P; Federal University of Rio de Janeiro State. Division of Pulmonary Medicine. Rio de Janeiro. BR
  • Carvalho, Carlos Roberto Ribeiro; University of São Paulo. School of Medicine. Hospital das Clinicas. Heart Institute. São Paulo. BR
Braz. j. infect. dis ; 11(1): 142-148, Feb. 2007. ilus
Artículo en Inglés | LILACS | ID: lil-454693
ABSTRACT
Leptospirosis is a re-emerging zoonosis occurring as large outbreaks throughout the world caused by Leptospira interrogans. The incidence of pulmonary involvement in leptospirosis has been reported to be increasing in the last years, affecting up to 70 percent of the patients. Alveolar hemorrhage presented as dyspnea and hemoptysis is the main pulmonary manifestation. The emergence of massive hemoptysis and acute respiratory distress syndrome has characterized the recent changes reported in the clinical patterns of leptospirosis. The pulmonary involvement has been emerged as a serious life threat, becoming the main cause of death due to leptospirosis in some countries. In this review we present the main clinical and pathological manifestations of pulmonary involvement in leptospirosis, with special focus on recent data concerning the pathophysiological mechanisms underlying lung injury.
Asunto(s)
Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Alveolos Pulmonares / Leptospirosis / Enfermedades Pulmonares Tipo de estudio: Revisiones Sistemáticas Evaluadas Límite: Animales / Humanos Idioma: Inglés Revista: Braz. j. infect. dis Asunto de la revista: Enfermedades Transmisibles Año: 2007 Tipo del documento: Artículo País de afiliación: Brasil Institución/País de afiliación: Federal University of Rio de Janeiro State/BR / University of São Paulo/BR

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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Alveolos Pulmonares / Leptospirosis / Enfermedades Pulmonares Tipo de estudio: Revisiones Sistemáticas Evaluadas Límite: Animales / Humanos Idioma: Inglés Revista: Braz. j. infect. dis Asunto de la revista: Enfermedades Transmisibles Año: 2007 Tipo del documento: Artículo País de afiliación: Brasil Institución/País de afiliación: Federal University of Rio de Janeiro State/BR / University of São Paulo/BR